
PANS / PANDAS Diagnosis and Treatment
Led by renowned PANDAS specialists Dr. Denis Bouboulis, Advanced Allergy provides expert diagnosis and treatment for pediatric autoimmune syndrome diagnosis and treatment.
Don’t wait to get the care your child needs. Dr. Bouboulis and our team are here to help you navigate your child's journey to a healthier future.
About Dr. Bouboulis

Advanced Allergy is led by Dr. Denis Bouboulis, dedicated to delivering expert care for the pediatric treatment of patients with PANDAS disease syndrome.
A renowned leader of PANDAS syndrome diagnosis and treatment, with over 15 years of experience diagnosis and treating this disease, Dr. Bouboulis is committed to helping patients with PANDAS reclaim their health and well-being via a wide range of therapies.
Dr. Bouboulis earned a national reputation for his innovative approach to PANDAS over the years, including his work on the widely publicized "Sneezing Girl" case, a groundbreaking diagnosis and treatment for a challenging PANDAS case that had baffled all prior experts and doctors at that time.
Contact Advanced Allergy to schedule a discussion today, and start your way to long-term health and recovery.
Patient Feedback
"After suffering with Lyme disease for years, I finally found Dr. Bouboulis. He has helped me tremendously and is also treating my husband for Lyme symptoms as well. Would highly recommend him!!"
- Vicki B
New Caanaan, CT
"I would like to let you know that Dr. Bouboulis is a caring and compassinate doctor who is always available when an issue occurs. He is genuinely concerned about his patients and is a doctor who listens to ideas."
- Stephanie S
Buffalo, NY
"Dr. Bouboulis has very effectively treated 3 members of our family for lyme and associated serious co-infections. His knowledge and expertise in these areas is unmatched. He is a caring, thoughtful practitioner obsessively concerned with his patient's well-being. He is the finest specialist we have ever had the good fortune to work with."
- Pete O
New Canaan, CT
"Our son has been a patient of Dr. Bouboulis for two years now. He has never made us feel rushed and meets all our concerns during every appointment. Our family's experience with Dr. Bouboulis has been very positive. That makes all the difference in my son's treatment."
- M. Wheeler
Trumbull, CT
"There are certain doctors that see beyond text books as science and medicine evolves and the human body is finally treated as a whole. Dr. B is a true pioneer who from day one agreed that we are dealing with post infection encephalitis, and thanks to his open mind both my girls are under the correct medical care.
- Anita S
Danbury, CT
"Well.. He's amazing. He did a thorough exam and explained everything to me after examining me. I had a lot of questions and he took the time to answer all of them, and he also made me feel comfortable to ask about further action to prevent further infections.
- Alex R
Bronx, NY

Our Services
PANDAS
Dr. Bouboulis, a nationally recognized expert in PANDAS, treating hundreds of patients successfully over the years.
Our comprehensive approach includes cutting-edge immunological therapies to help your child return to their best self. Let us guide you through a challenging diagnosis with compassion and expertise.
Lyme Disease Care
Living with Lyme disease can be overwhelming, but you're not alone.
At Advanced Allergy, we specialize in diagnosing and treating the complexities of Lyme disease and co-infections such as Babesiosis and Anaplasmosis.
Regain control over your health with our personalized care plans.
Autoimmune Deficiencies
Advanced Allergy is dedicated to managing and treating autoimmune deficiencies through innovative therapies.
Whether you’re newly diagnosed or seeking solutions for chronic symptoms, we’re here to improve your quality of life.

