About Dr. Bouboulis

Advanced Allergy is led by Dr. Denis Bouboulis, dedicated to delivering expert care for Lyme disease
A renowned leader of Lyme disease diagnosis and treatment, with over 15 years of experience in the diagnosis and treatment, Dr. Bouboulis is committed to helping patients with Lyme disease
For over 15 years, leading Lyme disease specialist Dr. Denis Bouboulis has provided expert care to patients throughout Connecticut and surrounding areas. At Advanced Allergy, we have helped hundreds of individuals manage and reclaim their health and well-being via a wide range of therapies.
Our customized Lyme disease therapy programs are designed to address both the infection and immune system deficiencies, promoting long-term health and sustainable recovery.
Contact Advanced Allergy to schedule a discussion today, and start your way to long-term health and recovery.
Patient Feedback
"After suffering with Lyme disease for years, I finally found Dr. Bouboulis. He has helped me tremendously and is also treating my husband for Lyme symptoms as well. Would highly recommend him!!"
- Vicki B
New Caanaan, CT
"I would like to let you know that Dr. Bouboulis is a caring and compassinate doctor who is always available when an issue occurs. He is genuinely concerned about his patients and is a doctor who listens to ideas."
- Stephanie S
Buffalo, NY
"Dr. Bouboulis has very effectively treated 3 members of our family for lyme and associated serious co-infections. His knowledge and expertise in these areas is unmatched. He is a caring, thoughtful practitioner obsessively concerned with his patient's well-being. He is the finest specialist we have ever had the good fortune to work with."
- Pete O
New Canaan, CT
"Our son has been a patient of Dr. Bouboulis for two years now. He has never made us feel rushed and meets all our concerns during every appointment. Our family's experience with Dr. Bouboulis has been very positive. That makes all the difference in my son's treatment."
- M. Wheeler
Trumbull, CT
"There are certain doctors that see beyond text books as science and medicine evolves and the human body is finally treated as a whole. Dr. B is a true pioneer who from day one agreed that we are dealing with post infection encephalitis, and thanks to his open mind both my girls are under the correct medical care.
- Anita S
Danbury, CT
"Well.. He's amazing. He did a thorough exam and explained everything to me after examining me. I had a lot of questions and he took the time to answer all of them, and he also made me feel comfortable to ask about further action to prevent further infections.
- Alex R
Bronx, NY

Our Services
PANDAS
Dr. Bouboulis, a nationally recognized expert in PANDAS, treating hundreds of patients successfully over the years.
Our comprehensive approach includes cutting-edge immunological therapies to help your child return to their best self. Let us guide you through a challenging diagnosis with compassion and expertise.
Lyme Disease Care
Living with Lyme disease can be overwhelming, but you're not alone.
At Advanced Allergy, we specialize in diagnosing and treating the complexities of Lyme disease and co-infections such as Babesiosis and Anaplasmosis.
Regain control over your health with our personalized care plans.
Autoimmune Deficiencies
Advanced Allergy is dedicated to managing and treating autoimmune deficiencies through innovative therapies.
Whether you’re newly diagnosed or seeking solutions for chronic symptoms, we’re here to improve your quality of life.